Hypothesis testing on point processes has several applications such as model fitting, plasticity detection, and non-stationarity detection. Standard tools for hypothesis testing include tests on mean firing rate and time varying rate function. However, these statistics do not fully describe a point process and thus the tests can be misleading. In this paper, we introduce a family of non-parametric divergence measures for hypothesis testing. We extend the traditional Kolmogorov--Smirnov and Cramer--von-Mises tests for point process via stratification.

MatKG is autonomously generated through transformer-based, large language models and generates pseudo ontological schema through statistical co-occurrence mapping. At present, MatKG contains over 2 million unique relationship triples derived from 80,000 entities. This allows the curated analysis, querying, and visualization of materials knowledge at unique resolution and scale. Further, Knowledge Graph Embedding models are used to learn embedding representations of nodes in the graph which are used for downstream tasks such as link prediction and entity disambiguation. MatKG allows the rapid dissemination and assimilation of data when used as a knowledge base, while enabling the discovery of new relations when trained as an embedding model.

Hypothesis testing on point processes has several applications such as model fitting, plasticity detection, and non-stationarity detection. Standard tools for hypothesis testing include tests on mean firing rate and time varying rate function. However, these statistics do not fully describe a point process and thus the tests can be misleading. In this paper, we introduce a family of non-parametric divergence measures for hypothesis testing. We extend the traditional Kolmogorov--Smirnov and Cramer--von-Mises tests for point process via stratification.

Sodium entry during an action potential determines the energy efficiency of a neuron. The classic Hodgkin-Huxley model of action potential generation is notoriously inefficient in that regard with about 4 times more charges flowing through the membrane than the theoretical minimum required to achieve the observed depolarization. Yet, recent experimental results show that mammalian neurons are close to the optimal metabolic efficiency and that the dynamics of their voltage-gated channels is significantly different than the one exhibited by the classic Hodgkin-Huxley model during the action potential. Nevertheless, the original Hodgkin-Huxley model is still widely used and rarely to model the squid giant axon from which it was extracted. Here, we introduce a novel family of Hodgkin-Huxley models that correctly account for sodium entry, action potential width and whose voltage-gated channels display a dynamics very similar to the most recent experimental observations in mammalian neurons. We speak here about a family of models because the model is parameterized by a unique parameter the variations of which allow to reproduce the entire range of experimental observations from cortical pyramidal neurons to Purkinje cells, yielding a very economical framework to model a wide range of different central neurons. The present paper demonstrates the performances and discuss the properties of this new family of models.

Hypothesis testing on point processes has several applications such as model fitting, plasticity detection, and non-stationarity detection. Standard tools for hypothesis testing include tests on mean firing rate and time varying rate function. However, these statistics do not fully describe a point process and thus the tests can be misleading. In this paper, we introduce a family of non-parametric divergence measures for hypothesis testing. We extend the traditional Kolmogorov--Smirnov and Cramer--von-Mises tests for point process via stratification. The proposed divergence measures compare the underlying probability structure and, thus, is zero if and only if the point processes are the same. This leads to a more robust test of hypothesis. We prove consistency and show that these measures can be efficiently estimated from data. We demonstrate an application of using the proposed divergence as a cost function to find optimally matched spike trains.